Vol. 2, Issue 1, Part A (2025)

Rasaushadhis, the herbo-mineral preparations in Ayurveda, represent a unique fusion of traditional pharmaceutical wisdom and alchemical transformation. The procedures of Bhavana (levigation) and Marana (calcination/incineration) form the core of these formulations, ensuring that potent minerals and metals are detoxified, potentiated, and rendered therapeutically active. These techniques have been refined through centuries of empirical observation and classical textual codification. This paper critically examines the scientific rationale, textual foundations, and pharmacological transformations involved in Bhavana and Marana. It further explores their implications for modern pharmaceutical science, challenges in standardization, and relevance in contemporary therapeutics, offering a holistic evaluation grounded in both classical Rasaśāstra and modern scientific insights.